Comprimé à 100 mg/10 mg (avec « 647 », une barre de confort sur une face, et uni sur l'autre face. La barre de cassure permet seulement de faciliter la prise du comprimé et n'est pas destinée à briser le comprimé en deux doses égales ; ovale, tacheté bleu foncé) : Boîte de 100, sous plaquettes. Comprimé sécable à 250 mg/25 mg (avec « 654 », une barre de sécabilité. SINEMET 25-250, containing 25 mg of carbidopa and 250 mg of levodopa. Inactive ingredients are hydroxypropyl cellulose, pregelatinized starch, crospovidone, microcrystalline cellulose, and magnesium stearate. SINEMET 10-100 and 25-250 Tablets also contain FD&C Blue 2/Indigo Carmine AL. SINEMET 25-100 Tablets also contain D&C Yellow 10 Lake. SINEMET CR contains either 50 mg of carbidopa and 200 mg of levodopa, or 25 mg of carbidopa and 100 mg of levodopa in a sustained-release dosage form designed to release these ingredients over a 4- to 6-hour period. With SINEMET CR there is less variation in plasma levodopa levels than with SINEMET® (carbidopa levodopa) immediate release tablets, the conventional formulation. You should not use Sinemet if you have narrow-angle glaucoma. Do not use Sinemet if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine. Before taking this medicine. You should not use Sinemet if you are allergic to carbidopa or levodopa, or if you have: Sinemet CR tablets contain either 50 mg of carbidopa and 200 mg of levodopa, or 25 mg of carbidopa and 100 mg of levodopa. How Sinemet works The underlying cause for the tremors, stiffness, and slowness of movements associated with Parkinson’s disease is the reduced level of dopamine (a neurotransmitter molecule) in the brain. SINEMET tablets are available in a 1:4 ratio of carbidopa to levodopa (SINEMET 25/100) as well as a 1:10 ratio (SINEMET 25/250). Tablets of the two ratios may be given separately or combined as needed to provide the optimum dosage. The tablet score-line for SINEMET 25/100 is only tofacilitate breaking for ease of swallowing Find patient medical information for Sinemet oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Sinemet 25-100 side effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common. Twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs. Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa. It is primarily used to manage the symptoms of Parkinson's disease, but it does not slow down the disease or stop it from getting worse. It is taken by mouth. It can take two to three weeks of treatment before benefits are seen. Sinemet 12.5 mg/50 mg: Do not store above 25°C. Store in the original package in order to protect from light. Sinemet 10 mg/100 mg: This medicinal product does not require any special storage conditions. Sinemet Plus 25 mg/100 mg, Sinemet 25 mg/250 mg: Do not store above 25°C. Store in the original package to protect from light and moisture.